Publications

Sheila Mathias, PhD

K Klepner, S Mathias, J Gudin, I Uchegbu. 28-Day Intranasal Toxicity Study of MMS019 in Sprague Dawley Rats & Dogs: 2024 SOT Annual Meeting and Tox Expo, Salt Lake City, UT (Abstract)

R Nandre, T Moir-Savits, B Sparrow, I Uchegbu, S Mathias, P Terse. Dose Range Finding Toxicity Study of NES100 following once daily Intranasal Administration for 14 Days in Dogs: 2025 SOT Annual Meeting and Tox Expo, Orlando FL (Abstract)

J Gudin, S Mathias, I Uchegbu. Leucine-Enkephalin as a Novel Analgesic: 3rd Annual Investigator Initiated HEAL Initiative Conference 2022.  Efficacy and Safety in Pre-Clinical Models.  (Abstract)

J Gudin, S Mathias, I Uchegbu. Enkephalin as a Novel Analgesic: Efficacy and Safety in Pre-Clinical Models. World Institute of Pain 2022 Budapest, Hungary (Poster)

J Gudin, S Mathias, I Uchegbu. Enkephalin as a Novel Analgesic: Efficacy and Safety in Pre-Clinical Models. PAIN Week 2022. Las Vegas, Nevada (Poster)

Brown, D.E., Mathias, S.A., Huron, D., Syapin, P.J., Stocco, D.M., and Mrotek, J.J. (April 1999). Nitric Oxide Synthase Located in Y-1 Mouse Adrenal Tumor Cells is Dependent on Calcium Ions for Modulating the Ability to Synthesize and Secrete Steroid Hormones, PE-474.

Mathias, S.A., Stocco, D., and Mrotek, J. (1998). Cd++ Inhibits Ca++ Dependent Steroid Secretion and Putative Nitric Oxide Production by Y-1 Adrenal Cell, FASEB 12:A1036.

Mathias, S.A., and Mrotek, J.J. (1997). Nitric Oxide Causes Age-Related Decreased 20DHP Secretion By Cultured Y-1 Adrenal Cells, Endocrine Society, 1997, Minneapolis, MN.

Mathias, S.A., and Mrotek, J.J. (1997). Characterizing the Nitric Oxide (NO) Pathway that Inhibits Y-1 Mouse Adrenal Cell Steroid Secretion, ICBMB, 1997, San Francisco, CA.

Parker, C., Mathias, S.A., and Mrotek, J.J. (1997). Cadmium Salt Modulation of Adrenal Cell Functions: Cadmium Acetate (CdAc2) Effects on Basal and dbcAMP Stimulated Steroid Secretion, Experimental Biology 197.11:A524.

Mathias, S.A., and Mrotek, J.J. (1997). Nitric Oxide (NO) Inhibits Y-1 Mouse Adrenal Cell Steroid Secretion, Experimental Biology 197.11:A77.

Mathias, S., Owens, J.R., and Mrotek, J. (1995). Evaluating Hemoglobin Effects on Cultured Adrenocortical Tumor Cell Steroid Secretion, FASEB.

Mathias, S.A., Wei, L., Hunter, E., Wells, O., Mgbonyebi, O., and Mrotek, J. (1994). Optimizing ACTH-Stimulated Steroid Secretion by Cultured Adrenocortical Tumor Cells, Ninth International Congress on Hormonal Steroids 9:88.

C. Smothers, O. Mgbonyebi, S. A. Mathias, L. Wei, E. Motley, and J. Mrotek (1994). Cadmium Ions Inhibit Stimulated Adrenal Cell Steroid Secretion By Competing with Calcium, FASEB 8:296.

Mathias, S.A., Wei, L., Mgbonyebi, O., and Mrotek, J. (1994). Cd++ Reduced Steroid Secretion by Cultured Adrenocortical Cells Used As Stress Models, First World Congress on Stress, 1:62.

Mathias, S.A., Wei, L., Hunter, E., Wells, O., Mgbonyebi, O., and Mrotek, J. (1994). Evaluating Cultured Y-1 Adrenocortical Tumor Cell Steroid Secretion Stimulators and Inhibitors, The American Society for Cell Biology, 5:393.

Mathias, S.A., Mgbonyebi, L.Wei, and J. Mrotek (1993). Does Diaphorase Perform Other Functions During Y-1 Adrenal Tumor Cell, Steroidogenesis, Molecular Biology of the Cell, 4:424

Matthew Barnes

Ratjen F, Durham T, Navratil T, Schaberg A, Accurso FJ, Wainwright C, Barnes M, Moss RB. Long term effects of denufosol tetrasodium in patients with cystic fibrosis. J Cyst Fibros.

Klein P, Biton V, Dilley D, Barnes M, Schiemann J, Lu S. Safety and tolerability of adjunctive brivaracetam as intravenous infusion or bolus in patients with epilepsy. Epilepsia. 2016 Jul;57(7):1130-8. doi: 10.1111/epi.13409. PubMed PMID: 27221208. 2012 Dec;11(6):539-49.

Joint Papers

Mathias S, Barnes M. Effective Partnering between Small Biopharmaceutical Companies and Their Service Providers: A Model that works. DIA Global Forum Jul 2023.

Barnes M, Mathias S. A Practical Approach to Risk Management During Drug Development. DIA Global Forum Jan 2025.

Barnes M, Mathais S. Synergies between Program Management and Regulatory to Mitigate Risks. DIA Global Forum Jan 2025.

Barnes M, Mathais S. Picking the Right Sized Partner. Outsourcing in Clinical Trials Handbook 2025